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| Martins,Alex Tadeu; Santos,Fabiano de Sant´Ana dos; Scannavino,Fábio Luiz Ferreira; Pires,Juliana Rico; Zuza,Elizângela Partata; Junior,João Armando Padovani; Azoubel,Reinaldo; Di Mateo,Miguel Angel Sala; Lopes,Ruberval Armando. |
| The cyclamate, a sweetner substance derived from N-cyclo-hexyl-sulfamic acid, is largely utilized as a non-caloric artificial edulcorant in foods and beverages as well as in the pharmaceutical industry. The objective of this study was to evaluate karyometric and stereological alterations in the rat fetal pancreas resulting from the intraperitoneal administration of sodium cyclamate. The exocrine pancreas of ten fetuses of rats were evaluated, five treated and five controls chosen at random, in which five rats that received from the 10th to 14th days of pregnancy an intraperitoneal daily injection of sodium cyclamate at 60 mg/Kg of body weight during 5 days. At the 20th day of gestation, the animals were removed and weighed, as were their placentas; the... |
| Tipo: Journal article |
Palavras-chave: Sodium cyclamate; Exocrine pancreas; Karyometry; Stereology. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300038 |
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| Martins,Alex Tadeu; Azoubel,Reinaldo; Lopes,Ruberval A.; di Matteo,Miguel A. Sala; de Arruda,José Germano Ferraz. |
| The cyclamate, a sweetner substance derived from N-cyclo-hexyl-sulfamic acid, is largely utilized as a non-caloric artificial edulcorant in foods and beverages as well as in the pharmaceutical industry. The objective of this study was to evaluate fetal hepatic karyometric and stereological alterations in the rat fetal liver resulting from the intraperitoneal administration of sodium cyclamate. The livers of ten rats were evaluated, five treated and five controls chosen at random, in which five rats that received from the 10th to 14th days of pregnancy an intraperitoneal daily injection of sodium cyclamate at 60 mg/Kg of body weight during 5 days. At the 20th day of gestation, the animals were removed and weighed, as were their placentas, on a precision... |
| Tipo: Journal article |
Palavras-chave: Sodium cyclamate; Fetal liver; Karyometry; Stereology. |
| Ano: 2005 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000300005 |
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| Accioly,Marilita Falângola; Souza,Dorotéia Rossi Silva; Padulla,Susimary Aparecida Trevizan; Camargo Filho,José Carlos Silva; do Carmo,Edna Maria; Martins,Alex Tadeu; Brandão,Antônio Carlos; Azoubel,Reinaldo. |
| The present study was carried out to evaluate the effect of statins associated with physical exercise (PE) in liver cells in dyslipidemic rats through cariometry. The animals were divided into six groups: animals subjected to a hypercholesterolemic diet (HD), simvastatin, with (G1) and without (G2) physical exercise (PE); HD submitted (G3) or not (G4) to PE, and commercial food diet (F) with (G5) and without (G6) PE. Histological analysis of the liver was performed by staining the slides with hematoxylin and eosin. The cariometric study included measuring the major and minor diameters of the hepatocytes nuclei. The Shapiro-Wilk test was also performed. To determine the differences among the groups, the Kruskal-Wallis Test with Dunn's post-test were... |
| Tipo: Journal article |
Palavras-chave: Simvastatin; Exercise; Diet; Cariometry. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400026 |
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| de Matos,Marcelo Alexandre; Martins,Alex Tadeu; Azoubel,Reinaldo. |
| To evaluate the effects of sodium cyclamate on the rat placenta by its administration in the period of embryogenesis. The sodium cyclamate was administered by intraperitoneal route in rats of the treated group at the dose of 60 mg/Kg, from the tenth to fourteenth day of gestation, while the equivalent volume of saline solution was given to the control group, by the same route. On the twentieth day of pregnancy, 10 fetuses (5 from each group) were chosen at random for study. The technique of cariometry was utilized for evaluation of nuclear parameters of cells in deciduous and spongy layers, and of chorionic villi in the rat placenta. The weights of treated fetuses and their placentas were less than those of the control group, while umbilical-cord length in... |
| Tipo: Journal article |
Palavras-chave: Sodium cyclamate; Placenta; Cariometry. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000300001 |
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| Curi,Viviane; Azoubel,Reinaldo; Lopes,Ruberval Armando; Martins,Alex Tadeu; Sala Di Matteo,Miguel Ángel; Kassis,Elias Naim. |
| The present work studied the adverse effects of maternal exposure of rats to alcohol during lactation, on the development of their off spring. Histometric evaluation by karyometry and of the alveolar bone at the level of the first upper molar of the sucking was perfomed. Two groups of animáis, one coming from mothers exposed to drinking water containing 20% ethanol during the total lactation period and the other of controls coming from mothers receiving only alcohol-free drinking water during this period. On the 21 first day of lactation the young of each group were aleatorily selected and following anesthesia, their heads severed; after histological treatment, serial 6 μm sections on the frontal plañe at the molar level, stained with hematoxilin... |
| Tipo: Journal article |
Palavras-chave: Ethanol; Alveolar bone; Lactation. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400026 |
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| Kassis,Elias Nairn; Azoubel,Reinaldo; Lopes,Ruberval Armando; Martins,Alex Tadeu; Matteo,Miguel Ángel Sala di; Gawlinski,Viviane Curi. |
| The present work studied the adverse effects of maternal exposure of rats to alcohol during lactation, on the development of their offspring. Histometric evaluation by karyometry and of the palatine epithelium of the sucking was performed. Two groups of animals, one coming from mothers exposed to drinking water containing 20% ethanol during the total lactation period and the other of controls coming from mothers receiving only alcohol-free drinking water during this period. On the 21 first day of lactation the young of each group were aleatorily selected and following anesthesia, their heads severed; after histological treatment, serial 6 |J,m sections on the frontal plane at the molar level, stained with hematoxilin and eosin, were obtained. The... |
| Tipo: Journal article |
Palavras-chave: Ethanol; Palatine epithelium; Lactation. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400013 |
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| Padovani Junior,João Armando; Azoubel,Reinaldo; Martins,Alex Tadeu; Maniglia,José Victor. |
| Laryngeal neoplasms represent 2% of all human cancers. They befall mainly the male sex, especially between 50 and 70 years of age, but exceptionally may occur in infancy or extreme old age. Their occurrence has increased considerably inclusively due to progressive population again. The present work aims at establishing a relation between this infirmity and its prognosis in patients submitted to the treatment recommended by Departament of Otolaryngology and Head Neck Surgery of the School of Medicine of São José do Rio Preto. To this effect, by means of karyometric optical microscopy, cell nuclei in the glottic region of 20 individuals, divided into groups according to their tumor stage and time of survival, were evaluated. Following comparation with a... |
| Tipo: Journal article |
Palavras-chave: Morphometry; Laryngeal neoplasms. |
| Ano: 2005 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000300015 |
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